gas gangrene

 Gas Gangrane

Gas gangrene is highly infectious disease caused by bacteria clostridium perfringens.

Gas gangrene is a bacterial infection, characterized by necrotizing soft tissue of skeletal muscle and  production of foul-smelling gas. This bacteria clostridium perfringens grow only in the absence of oxygen.

This bacteria release gas and harmful substances that damage body tissues, blood vessels.

Gas gangrane usually occurs at the site of trauma or a recent surgical wound, any injury.

The bacterial infection produces toxins that release gas and cause tissue necrosis.

Gas Gangrane infection is most commonly affects the arms or legs.

Causative Agent; Clostridium perfringens

Etiology

1. Lack of blood supply

2. Untreated bacterial infection

3. Traumatic injury

4. Injury or surgical wound 

Clinical Manifestation

1. Drainage from the tissues

2. Foul-smelling/ subcutaneous gas

3. Blisters

3. Skin turned Brown-red 

4. Moderate to severe pain around a skin injury

5. Tenderness

6. Local swelling to massive edema

Pathophysiology

Bacterial infection occurs in at site of injury

Bacteria make a colony and grow inside the body

Bacteria emits gas and release toxins

Damaging the body tissues and blood vessels

Lab Diagnosis

1. X-rays

2. Computerized tomography (CT) scans

3. Magnetic resonance imaging (MRI) scans

4. Gas bubbles in muscle tissue 

5. Performing a tissue biopsy

Prevention

1. Clean wounds thoroughly

2. Remove foreign objects and dead tissue from wounds.

Treatment

Antibiotics; metronidazole

Surgical debridement

Hyperbaric oxygen therapy